All eyes will be on QBs Brock Purdy and Patrick Mahomes when the San Francisco 49ers (3-3) and Kansas City Chiefs (5-0) play on Oct. 20. Which signal-caller is better equipped to bring home a win in this matchup? We break it all down below.

At 2-3 overall and 0-2 in the NFC West division, a loss to the Seahawks wouldn't have buried the 49ers' season but it would have dug the hole plenty deep. Even as things piled up against San Francisco on Thursday night in Seattle -- more injuries,

Jordan Mason sprained the AC joint shoulder Thursday during the 49ers' 36-24 win over the Seahawks. He returned to the game for one play, ran the bal

Mason has 10 days to prepare for the 49ers' Week 7 matchup against the undefeated Kansas City Chiefs. If Mason isn't able to suit up, the 49ers will rely on rookie running back Isaac Guerendo and fourth-year running back Patrick Taylor Jr.

The San Francisco 49ers have avoided the worst-case scenario with running back Jordan Mason. 49ers head coach Kyle Shanahan told reporters Friday that

Some of the dramatics in the San Francisco 49ers’ Week 6 win over the Seattle Seahawks could have been ratcheted down had the NFL’s replay review system operated properly. In the fourth quarter the Seahawks cut the 49ers’ 20-point lead to 6 with back-to-back touchdowns.

When Geno Smith stepped to the microphone after another gut-punch of a loss for the Seahawks, this one a 36-24 home defeat to division rival San Francisco, he wasn’t about make any excuses. “Obviously we did a lot of things that you don’t want to do when you talk about winning football games,

One big storyline from Thursday's Seahawks loss was a 49ers challenge that appeared to have been ruled incorrectly because the NFL wasn't provided the best video by Amazon.